Exelixis
/install exelixis
Exelixis
历史时间线
- 1994: Founded in Alameda, California
- 2000s: Pioneers small-molecule kinase inhibitor discovery platform
- 2012: FDA approves cabozantinib (Cometriq) for medullary thyroid cancer
- 2016: Cabometyx approved for advanced renal cell carcinoma
- 2019: HCC indication approved (liver cancer)
- 2021: COSMIC-313 trial shows combination therapy benefit
- 2023: Revenue $2.2B, expanding into new oncology indications
- 2024: Pipeline expansion beyond cabozantinib
商业模式
Focused oncology company centered on cabozantinib (Cabometyx), a multi-kinase inhibitor targeting MET, VEGFR2, and AXL. Revenue from Cabometyx sales across kidney cancer, liver cancer, and thyroid cancer. Pipeline includes next-generation kinase inhibitors and combination therapies with immunotherapy.
护城河分析
Cabozantinib's multi-kinase targeting creates broader efficacy than single-target competitors. Expanded label across three cancer types diversifies revenue. Long patent life with potential extensions through combination indications.
关键数据
- Founded: 1994, Alameda, California
- Revenue 2023: ~$2.2B
- Employees: ~800
- Flagship Drug: Cabometyx (cabozantinib)
- Indications: Renal Cell Carcinoma, Hepatocellular Carcinoma, Thyroid Cancer
有趣事实
- Exelixis's name comes from 'helix' (DNA) and the Greek prefix for 'evolution' — reflecting their focus on evolving cancer treatments.
- Cabozantinib was originally developed for thyroid cancer but found its biggest commercial success in kidney and liver cancer — a classic example of drug repurposing.
- 确保已安装 OpenClaw(本地或 Docker 部署)
- 在对话框中输入安装命令:
/install exelixis - 安装完成后,直接呼叫该 Skill 的名称或使用
/exelixis触发 - 根据 Skill 的参数说明提供必要输入,即可获得结构化输出
Exelixis 是什么?
Exelixis develops cabozantinib-based multi-kinase inhibitors for kidney, liver, and thyroid cancers, focusing on oncology combination therapies and pipeline... 它是一个面向 Claude Code / OpenClaw 的 AI Agent Skill 插件,目前累计下载 73 次。
如何安装 Exelixis?
在 OpenClaw 或 Claude Code 对话框中运行命令「/install exelixis」即可一键安装,无需额外配置。
Exelixis 是免费的吗?
是的,Exelixis 完全免费,采用 MIT-0 许可证,可自由下载、安装和使用。
Exelixis 支持哪些平台?
Exelixis 跨平台运行,可在任意部署了 OpenClaw / Claude Code 的环境中使用(cross-platform)。
谁开发了 Exelixis?
由 hanxueyuan(@hanxueyuan)开发并维护,当前版本 v1.0.0。