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hanxueyuan

Exelixis

by hanxueyuan · GitHub ↗ · v1.0.0 · MIT-0
cross-platform ✓ Security Clean
73
Downloads
0
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0
Active Installs
1
Versions
Install in OpenClaw
/install exelixis
Description
Exelixis develops cabozantinib-based multi-kinase inhibitors for kidney, liver, and thyroid cancers, focusing on oncology combination therapies and pipeline...
README (SKILL.md)

Exelixis

历史时间线

  • 1994: Founded in Alameda, California
  • 2000s: Pioneers small-molecule kinase inhibitor discovery platform
  • 2012: FDA approves cabozantinib (Cometriq) for medullary thyroid cancer
  • 2016: Cabometyx approved for advanced renal cell carcinoma
  • 2019: HCC indication approved (liver cancer)
  • 2021: COSMIC-313 trial shows combination therapy benefit
  • 2023: Revenue $2.2B, expanding into new oncology indications
  • 2024: Pipeline expansion beyond cabozantinib

商业模式

Focused oncology company centered on cabozantinib (Cabometyx), a multi-kinase inhibitor targeting MET, VEGFR2, and AXL. Revenue from Cabometyx sales across kidney cancer, liver cancer, and thyroid cancer. Pipeline includes next-generation kinase inhibitors and combination therapies with immunotherapy.

护城河分析

Cabozantinib's multi-kinase targeting creates broader efficacy than single-target competitors. Expanded label across three cancer types diversifies revenue. Long patent life with potential extensions through combination indications.

关键数据

  • Founded: 1994, Alameda, California
  • Revenue 2023: ~$2.2B
  • Employees: ~800
  • Flagship Drug: Cabometyx (cabozantinib)
  • Indications: Renal Cell Carcinoma, Hepatocellular Carcinoma, Thyroid Cancer

有趣事实

  • Exelixis's name comes from 'helix' (DNA) and the Greek prefix for 'evolution' — reflecting their focus on evolving cancer treatments.
  • Cabozantinib was originally developed for thyroid cancer but found its biggest commercial success in kidney and liver cancer — a classic example of drug repurposing.
Usage Guidance
This skill is informational only and does not request credentials or install software, so it appears safe to add from a system-privilege perspective. However, the skill's source/homepage is unknown and SKILL.md is a static summary — verify any clinical, financial, or regulatory claims against authoritative sources (company filings, peer-reviewed literature, FDA notices) before using the information for decisions, and do not treat it as medical advice.
Capability Analysis
Type: OpenClaw Skill Name: exelixis Version: 1.0.0 The skill bundle contains purely informational content regarding Exelixis, a biopharmaceutical company. There is no executable code, no network requests, and no prompt injection attempts within SKILL.md or _meta.json. The content is strictly educational and aligns with its stated purpose.
Capability Assessment
✓ Purpose & Capability
The skill's name and description match the SKILL.md content (company background, timeline, business analysis). It does not request unrelated resources or capabilities. Note: the skill's source/homepage is unknown, which limits verifiability but does not create an internal coherence problem.
✓ Instruction Scope
SKILL.md contains only static informational content and 'read_when' guidance for when to use it. It does not instruct the agent to read system files, access environment variables, or send data externally.
✓ Install Mechanism
No install spec and no code files — instruction-only. There is nothing written to disk or downloaded during install.
✓ Credentials
The skill declares no required environment variables, credentials, or config paths; requested privileges are minimal and proportional to an informational skill.
✓ Persistence & Privilege
always is false and the skill does not request persistent presence or modify other skills. disable-model-invocation is false (normal); autonomous invocation is allowed by platform default but this skill's read-only nature keeps risk low.
How to Use
  1. Make sure OpenClaw is installed (local or Docker)
  2. Run the install command in chat: /install exelixis
  3. After installation, invoke the skill by name or use /exelixis
  4. Provide required inputs per the skill's parameter spec and get structured output
Version History
v1.0.0
Exelixis skill initial release: - Provides an overview of Exelixis, a biopharmaceutical company focused on oncology. - Includes a company history timeline highlighting major drug approvals and milestones. - Outlines the business model, emphasizing Cabometyx and combination therapies. - Features a moat analysis summarizing competitive advantages. - Lists key facts and interesting insights about Exelixis and its flagship drug.
Metadata
Slug exelixis
Version 1.0.0
License MIT-0
All-time Installs 0
Active Installs 0
Total Versions 1
Frequently Asked Questions

What is Exelixis?

Exelixis develops cabozantinib-based multi-kinase inhibitors for kidney, liver, and thyroid cancers, focusing on oncology combination therapies and pipeline... It is an AI Agent Skill for Claude Code / OpenClaw, with 73 downloads so far.

How do I install Exelixis?

Run "/install exelixis" in the OpenClaw or Claude Code chat to install it in one step — no extra setup required.

Is Exelixis free?

Yes, Exelixis is completely free, licensed under MIT-0. You can download, install and use it at no cost.

Which platforms does Exelixis support?

Exelixis is cross-platform and runs anywhere OpenClaw / Claude Code is available (cross-platform).

Who created Exelixis?

It is built and maintained by hanxueyuan (@hanxueyuan); the current version is v1.0.0.

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