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Install in OpenClaw
/install two-sample-mr-research-planner
Description
Generates tailored two-sample Mendelian randomization study plans with four workload options, detailed workflows, validation, figures, and publication strate...
Usage Guidance
This skill is an instruction-only MR study planner and appears internally consistent. Before relying on outputs: (1) verify any specific dataset availability/dates and citations the planner cites (LLMs can hallucinate details); (2) do not paste unpublished or participant-level genetic/clinical data into the chat — the skill assumes summary-statistic-level planning only; (3) have an MR/statistics expert review final analysis plans and code before execution or publication; (4) if you plan to attach this skill to an agent that can fetch external GWAS files, review that agent's data-access behavior and ensure it uses authorized APIs and protects any sensitive tokens. Overall the skill is coherent for its stated purpose, but standard domain validation and data-handling care are still required.
Capability Analysis
Type: OpenClaw Skill
Name: two-sample-mr-research-planner
Version: 0.1.0
The skill is a specialized research planning tool for Mendelian Randomization (MR) studies in genetics and epidemiology. It provides structured workflows, scientific benchmarks for instrumental variables, and R code templates using standard, legitimate bioinformatics libraries like `TwoSampleMR` and `MRPRESSO`. The documentation (SKILL.md, gwas_databases.md, iv_benchmarks.md) contains accurate scientific guidance and links to reputable academic data portals (e.g., IEU Open GWAS, GWAS Catalog). No indicators of malicious intent, data exfiltration, or prompt injection were found.
Capability Assessment
Purpose & Capability
The name/description (two-sample MR research planner) matches the content: stepwise study designs, instrument benchmarks, GWAS source recommendations, and deliverables. Required binaries/env/configs are none, which is appropriate for a prose planning tool.
Instruction Scope
SKILL.md and the two reference files contain prescriptive guidance for designing MR studies (data selection, instrument thresholds, sensitivity analyses, figure plans). Instructions remain within the domain of study design and reporting; they reference external GWAS resources but do not tell the agent to read unrelated system files, access credentials, or transmit data to hidden endpoints.
Install Mechanism
No install spec and no code files — the skill is instruction-only, which minimizes on-disk risk. There are no downloads, third-party packages, or binaries requested.
Credentials
The skill declares no required environment variables, credentials, or config paths. The references point to public GWAS portals and literature; no disproportionate secret access is requested.
Persistence & Privilege
The skill does not request persistent or elevated privileges (always:false). It does not attempt to modify other skills or system settings; autonomous invocation is platform-default but this skill's content does not increase that risk.
How to Use
- Make sure OpenClaw is installed (local or Docker)
- Run the install command in chat:
/install two-sample-mr-research-planner - After installation, invoke the skill by name or use
/two-sample-mr-research-planner - Provide required inputs per the skill's parameter spec and get structured output
Version History
v0.1.0
two-sample-mr-research-planner v0.1.0
- Initial release: automatically generates complete two-sample Mendelian randomization (MR) study designs from a user-provided research direction.
- Always outputs four workload configurations (Lite, Standard, Advanced, Publication+) with detailed step-by-step workflow, figure plan, validation, minimal version, and upgrade path.
- Supports multiple MR study styles (single, multi-exposure, bidirectional, lifestyle, biomarker, publication-oriented) with clear input requirements.
- Integrates robust fault tolerance, explicit assumptions, IV count benchmarks, and reviewer risk review into every plan.
- Includes R code framework guidance using TwoSampleMR, with clear marking of example GWAS IDs.
Metadata
Frequently Asked Questions
What is Two Sample Mr Research Planner?
Generates tailored two-sample Mendelian randomization study plans with four workload options, detailed workflows, validation, figures, and publication strate... It is an AI Agent Skill for Claude Code / OpenClaw, with 237 downloads so far.
How do I install Two Sample Mr Research Planner?
Run "/install two-sample-mr-research-planner" in the OpenClaw or Claude Code chat to install it in one step — no extra setup required.
Is Two Sample Mr Research Planner free?
Yes, Two Sample Mr Research Planner is completely free, licensed under MIT-0. You can download, install and use it at no cost.
Which platforms does Two Sample Mr Research Planner support?
Two Sample Mr Research Planner is cross-platform and runs anywhere OpenClaw / Claude Code is available (cross-platform).
Who created Two Sample Mr Research Planner?
It is built and maintained by shanruoyu (@shanruoyu); the current version is v0.1.0.
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