SYRI 共线性分析

执行基因组间 SYRI 共线性分析，包含染色体处理、minimap2 比对、结构变异检测及 plotsr 可视化流程。

The skill appears to implement a legitimate SYRI analysis pipeline, but before installing/running it: 1) ensure the required tools (minimap2, syri, plotsr, Biopython) are actually installed — the registry metadata omits these requirements; 2) run inside a controlled conda environment to avoid polluting system Python; 3) avoid redirecting stderr into the SAM file (minimap2 stdout should be captured to the SAM file and stderr to logs); if you do capture both, be prepared to clean the SAM as shown; 4) be cautious with the recommended 64–120 threads — verify you have the CPU, memory, and I/O capacity, otherwise reduce thread count; 5) monitor backgrounded processes (they recommend using & and echo PID) to avoid orphaned jobs; 6) verify and test the chromosome renaming/mapping script on a small example before running on full genomes to avoid irreversible data mistakes; and 7) consider asking the skill author or maintainer to update the skill metadata to list required binaries and any recommended compute resources so the registry entry and SKILL.md are consistent.

Type: OpenClaw Skill Name: syri-analysis Version: 1.0.0 The skill bundle provides a legitimate and detailed workflow for genomic synteny analysis using standard bioinformatics tools like minimap2, SYRI, and plotsr. The included Python scripts and shell commands in SKILL.md are consistent with the stated purpose of processing FASTA files and performing structural variation analysis, with no evidence of malicious intent, data exfiltration, or prompt injection.