Alnylam Pharma
/install alnylam-pharma
历史时间线
- 2002 诺贝尔奖得主Phillip Sharp和Thomas Tuschl联合创立
- 2010 与赛诺菲达成30亿美元合作(后来终止回购权利)
- 2018 FDA批准Onpattro,全球首款RNAi药物
- 2019 推出Givlaari治疗急性肝卟啉症
- 2020 Oxlumo获批治疗原发性高草酸尿症
- 2022 Amvuttra获批,首个皮下注射siRNA,每3个月给药一次
- 2023 推出Leqvio(与诺华合作)降低胆固醇
商业模式
RNAi(RNA干扰)平台型公司,用siRNA沉默致病基因。核心策略:先用罕见病证明概念,后扩展到更常见病(如心血管疾病)。Leqvio是与诺华合作的降胆固醇药,潜在患者超数千万。
护城河分析
siRNA递送技术(GalNAc偶联)是其核心竞争力——能将药物精准递送到肝细胞,其他公司难以复制。已上市3款产品+数十个临床管线形成数据壁垒。
关键数据
- 2023年收入约12亿美元
- Leqvio峰值销售预测超30亿美元
- 全球员工约2,500人
- 市值约250亿美元
有趣事实
Alnylam的名字来自RNAi的字母重排。两位创始人都获得了2006年诺贝尔医学奖(RNAi发现)。
- Make sure OpenClaw is installed (local or Docker)
- Run the install command in chat:
/install alnylam-pharma - After installation, invoke the skill by name or use
/alnylam-pharma - Provide required inputs per the skill's parameter spec and get structured output
What is Alnylam Pharma?
Alnylam Pharma pioneers RNAi therapeutics with three approved siRNA drugs for rare genetic and cardiovascular diseases using GalNAc delivery technology. It is an AI Agent Skill for Claude Code / OpenClaw, with 4 downloads so far.
How do I install Alnylam Pharma?
Run "/install alnylam-pharma" in the OpenClaw or Claude Code chat to install it in one step — no extra setup required.
Is Alnylam Pharma free?
Yes, Alnylam Pharma is completely free, licensed under MIT-0. You can download, install and use it at no cost.
Which platforms does Alnylam Pharma support?
Alnylam Pharma is cross-platform and runs anywhere OpenClaw / Claude Code is available (cross-platform).
Who created Alnylam Pharma?
It is built and maintained by hanxueyuan (@hanxueyuan); the current version is v1.0.0.